國立台灣大學醫學院 醫學教育暨生醫倫理學科暨研究所
Department of Medical Education & Bioethics / Graduate Institute of Medical Education & Bioethics
National Taiwan University College of Medicine

2019 Lin CH, Li CH, Yang KC, Lin FJ, Wu CC, Chieh JJ, Chiu MJ. Blood NfL: A biomarker for disease severity and progression in Parkinson’s disease. Neurology. 2019 Sep 10;93(11):e1104-e1111. [PubMed Abstract]

2019 Lin JF, Wu CC, Liao YJ, Jakfar S, Tang ZB, Chen JK, Lin FH. In vitro and in vivo evaluations of mesoporous iron particles for iron bioavailability. Int J Mol Sci. 2019 Oct 24; 20(21). [PubMed Abstract]

2019 Lin KH, Huang SC, Wang CH, Wu CC, Chu TS and Chen YY. Physician workload associated with do-not- resuscitate decision-making in intensive care units: an observational study using Cox proportional hazards analysis. BMC Medical Ethics 2019;20:15. [PubMed Abstract]

2019 Lin CH, Liu HC, Yang ST, Yang KC, Wu CC, Chiu MJ. Plasma pS129-a-synuclein is a surrogate biofluid marker of motor severity and progression in Parkinson's disease. J Clin Med. 2019;8:1601-1-11. [PubMed Abstract]

2019 Lue LF, Pai MC, Chen TF, Hu CJ, Huang LK, Lin WC, Wu CC, Jeng JS, Blennow K, Sabbagh MN, Yan SH, Wang PN, Yang SY, Hatsuta H, Morimoto S, Takeda A, Itoh Y, Liu J, Xie H, and Chiu MJ. Age-dependent relationship between plasma Aβ40 and Aβ42 and total tau levels in cognitively normal subjects. Front Aging Neurosci., 2019; 11 (Article 222): 1-8. [PubMed Abstract]

2019 Hsu CY, Tseng WK, Wu YY, Lin TH, Yeh HI, Chang KC, Wang JH, Chou RH, Huang CY, Huang PH, Leu HB, Yin WH, Wu CC, Lin SJ, and Chen JW. Circulating TNFSF14 predicts clinical outcome in patients with stable coronary artery disease. Arterioscler Thromb Vasc Biol. 2019 Jun;39(6):1240-1252. [PubMed Abstract]

2019 Li YH, Chen JW, Lin TH, Wang YC, Wu CC, Yeh HI, Huang CC, Chang KC, Wu CK, Chen PW, Huang CW, Chen ZC, Chang WT, Huang WC, Wang CY, Lee MY, Chao AC, Fu WR, Tsai LK, Tang SC, Chan HL, Yang YC, Wu YW, Hwang JJ, Lin JL. A performance guide for major risk factors control in patients with atherosclerotic cardiovascular disease in Taiwan. J Formos Med Assoc. 2019 May 18. pii: S0929-6646(19)30003-8. doi: 10.1016/j.jfma.2019.04.007. [Epub ahead of print] Review. [PubMed Abstract]

2019 Wu JR, Leu HB, Yin WH, Tseng WK, Wu YW, Lin TH, Yeh HI, Chang KC, Wang JH, Wu CC, Chen JW. The benefit of secondary prevention with oat fiber in reducing future cardiovascular event among CAD patients after coronary intervention. Sci Rep. 2019 Feb 28;9(1):3091. [PubMed Abstract]

2018 Ho SK, Wu YW, Tseng WK, Leu HB, Yin WH, Lin TH, Chang KC, Wang JH, Yeh HI, Wu CC (Correspondence), Chen JW. The prognostic significance of heart-type fatty acid binding protein in patients with stable coronary heart disease. Sci Rep. 2018 Sep 26;8(1):14410.  [PubMed Abstract]

2018 Tang SC, Yang KC, Yang SY, Chiu MJ, Wu CC (Correspondence), Jeng JS. Plasma β-amyloids and Tau Proteins in Patients with Vascular Cognitive Impairment. Neuromol Med. 2018 Sep 21;20(12):1-6. [PubMed Abstract]

2018 Ho LT, Lin FJ Tseng WK, Yin WH, Wu YW, Li YH, Yeh HI, Chen JW, Wu CC (Correspondence), on behalf of the Taiwanese Secondary Prevention for Patients with AtheRosCLErotic Disease (T-SPARCLE) Registry Investigators. On-Treatment Lipid Profiles to Predict the Cardiovascular Outcomes in ASCVD Patients Comorbid with Chronic Kidney Disease--the Multi-Center T-SPARCLE Registry Study. J Formos Med Assoc. 2018 Jun 23;117:814-824. [PubMed Abstract]

2018 Shih YC, Chen CL, Zhang Y, Mellor RL, Kanter EM, Fang Y, Wang HC, Hung CT, Nong JY, Chen HJ, Lee TH, Tseng YS, Chen CN, Wu CC, Lin SL, Yamada KA, Nerbonne JM, Yang KC. Endoplasmic Reticulum Protein TXNDC5 Augments Myocardial Fibrosis by Facilitating Extracellular Matrix Protein Folding and Redox-Sensitive Cardiac Fibroblast Activation. Circ Res. 2018 Apr 13;122(8):1052-1068. [PubMed Abstract]

2017 Tang SC, Yang KC, Hu CJ, Chiou HY, Wu CC, Jeng JS. Elevated Plasma Level of Soluble Form of RAGE in Ischemic Stroke Patients with Dementia. Neuromol Med. 2017 Dec;19(4):579-583. [PubMed Abstract]

2017 Lee LH, Gallus A, Jindal R, Wang C, Wu CC. Incidence of Venous Thromboembolism in Asian Populations: A Systematic Review. Thromb Haemost. 2017 Dec;117(12):2243-2260. [PubMed Abstract]

2017 Ting PS, Chen LK, Yang WC, Huang TS, Wu CC, and Chen YY. Gender and age disparity in the initiation of life-supporting treatments: a population-based cohort study. BMC Medical Ethics. 2017 November 15;18:62. [PubMed Abstract]

2017 Yeh YT, Yin WH, Tseng WK, Lin FJ, Yeh HI, Chen JW, Wu YW, Wu CC (Correspondence), on behalf of the Taiwanese Secondary Prevention for Patients with AtheRosCLErotic Disease (T-SPARCLE) Registry Investigators. Lipid lowering therapy in patients with atherosclerotic cardiovascular diseases: Which matters in the real world? Statin intensity or low-density lipoprotein cholesterol level? – Data from a multicenter registry cohort study in Taiwan. PLoS ONE. 2017; 12(10): e0186861. [PubMed Abstract]

2017 Huang CC, Leu HB, Yin WH, Tseng WK, Wu YW, Lin TH, Yeh HI, Chang KC, Wang JH, Wu CC, Chen JW. Optimal achieved blood pressure for patients with stable coronary artery disease. Sci Rep. 2017 Aug 31;7(1):10137. [PubMed Abstract]

2017 Lin FJ, Tseng WK, Yin WH, Yeh HI, Chen JW, Wu CC (Correspondence). Residual Risk Factors to Predict Major Adverse Cardiovascular Events in Atherosclerotic Cardiovascular Disease Patients with and without Diabetes Mellitus. Sci Rep. 2017 Aug 23;7(1):9179. [PubMed Abstract]

2017 Yang SY*, Chiu MJ, Chen TF, Lin CH, Jeng JS, Tang SC, Lee YF, Yang CC, Liu BH, Chen HH, Wu CC. Analytical performance of reagent for assaying tau protein in human plasma and feasibility study screening neurodegenerative diseases. Sci Rep 2017; 7: 9304. [PubMed Abstract]

2017 Chien SC, Chen CY, Leu HB, Su CH, Yin WH, Tseng WK, Wu YW, Lin TH, Chang KC, Wang JH, Wu CC, Yeh HI*, Chen JW. Association of low serum albumin concentration and adverse cardiovascular events in stable coronary heart disease. Int J Cardiol. 2017 Aug; 241:1-5. [PubMed Abstract]

2017 Li YH, Ueng KC, Jeng JS, Charng MJ, Lin TH, Chien KL, Wang CY, Chao TH, Liu PY, Su CH, Chien SC, Liou CW, Tang SC, Lee CC, Yu TY, Chen JW, Wu CC, Yeh HI*. 2017 Taiwan lipid guidelines for high risk patients. J Formos Med Assoc 2017; 116(4): 217-248. [PubMed Abstract]

2017 Chen TE, Yang SI, Ho LT, Tsai KH, Chen YH, Chang YF, Lai YH, Wang SS, Tsao Y, Wu CC*. S1 and S2 Heart Sound Recognition Using Deep Neural Networks. IEEE Trans Biomed Eng 2017; 64(2): 372-380. [PubMed Abstract]

2017 Leu HB, Yin WH, Tseng WK, Wu YW, Lin TH, Yeh HI, Chang KC, Wang JH, Wu CC*, Chen JW. Identification of new biosignatures for clinical outcomes in stable coronary artery disease - The study protocol and initial observations of a prospective follow-up study in Taiwan. BMC Cardiovasc Disord 2017; 17(1): 42. [PubMed Abstract]

2016 Chen YY, Chen YS, Chu TS, Lin KH*, Wu CC*. Further deliberating the relationship between do-not-resuscitate and the increased risk of death. Scientific Reports 2016; 6: 23182. [PubMed Abstract]

2016 Yin WH, Chen P, Yeh HI, Wang KY, Hung YJ, Tseng WK, Wen MS, Wu TC, Wu CC, Cheng SM, Chen JW. Combination with low-dose Dextromethorphan improvesthe effect of Amlodipine monotherapy in clinical hypertension: a first-in-human, concept-proven, prospective, dose-escalation, multicenter study. Medicine (Baltimore) 2016; 95(12):e3234. [PubMed Abstract]

2016 Tseng FY, Hsieh JY, Kao TW, Wu CC, Chu TS, Chen YY*. Developing and evaluating medical humanities problem-based learning classes facilitated by the teaching assistants majored in the liberal arts: a longitudinal crossover study. Medicine (Baltimore) 2016; 95(6):e2765. [PubMed Abstract]

2016 Lin KH, Chen YS, Chou NK, Huang SJ, Wu CC, Chen YY*. The associations between the religious background, social supports and do-not-resuscitate orders in Taiwan: an observational study. Medicine (Baltimore) 2016; 95(3):e2571. [PubMed Abstract]

2015 Ho LT, Yin WH, Chuang SY, Tseng WK, Wu YW, Hsieh IC, Lin TH, Li YH, Huang LC, Wang KY, Ueng KC, Fang CC, Pan WH, Yeh HI, Wu CC*, Chen JW, on behalf of the Taiwanese Secondary Prevention for Patients with AtheRosCLErotic Disease (T-SPARCLE) Registry Investigators. Determinants for Achieving the LDL-C Target of Lipid Control for Secondary Prevention of Cardiovascular Events in Taiwan. PLoS One 2015;10:e0116513. [PubMed Abstract]

2015 Chang YC, Wu CC*, Lin CH, Wu YW, Yang YC, Chang TJ, Jiang YD, Chuang LM. Early myocardial repolarization heterogeneity is detected by magnetocardiography in diabetic patients with cardiovascular risk factors. PLoS One 2015;10:e0133192. [PubMed Abstract]

2015 Chen PH, Liao HC, Hsu SH, Chen RS, Wu MC, Yang YF, Wu CC*, Chen MH, Su WF. A novel polyurethane/cellulose fibrous scaffold for cardiac tissue engineering. RSC Adv 2015;9:6932-6939.

2014 Lin TH, Chuang SY, Chu CY, Lee WH, Hsu PC, Su HM, Li YH, Fang CC, Wang KY, Tseng WK, Li AH, Ueng KC, Hsieh IC, Huang LC, Wang CH, Pan WH, Yeh HI, Wu CC*, Yin WH, Chen JW. The Impact of Chronic Kidney Disease on Lipid Management and Goal Attainment in Patients with Atherosclerosis Diseases in Taiwan. Int J Med Sci 2014; 11(4): 381-388. [PubMed Abstract]

2014 Wu YW, Lin LC, Tseng WK, Liu YB, Kao HL, Lin MS, Huang HC, Wang SY, Horng HE, Yang HC, Wu CC. QT(c) Heterogeneity in Rest Magnetocardiography is Sensitive to Detect Coronary Artery Disease: In Comparison with Stress Myocardial Perfusion Imaging. Acta Cardiol Sin 2014;30:445-454. [PubMed Abstract]

2014 Huang KW, Yang SY, Horng HE, Chieh JJ, Chen HH, Wu CC*, Chen JH, Lin IT, Yang CC, Yang HC. Time-evolution Contrast of Target MRI Using High-stability Antibody Functionalized Magnetic Nanoparticles: An Animal Model. J Nanomater 2014:351848 (1-7).

2013 Yang SY, Chieh JJ, Yang CC, Liao SH, Chen HH, Horng HE, Yang HC, Hong CY, Chiu MJ, Chen TF, Huang KW, and Wu CC*. Clinic applications in assaying ultra-low-concentration bio-markers using HTS SQUID-based AC magnetosusceptometer. IEEE Trans.Appl Supercond 2013; 23,1600604.

2013 Chen CY, Chuang SY, Fang CC, Huang LC, Hsieh IC, Pan WH, Yeh HI, Wu CC*, Yin WH, Chen JW. Gender difference in statin intervention on blood lipid control among patients with coronary heart disease. Int J Gerontology 2013;7(2): 116-121.

2012 Tseng WK, Chieh JJ, Yang YF, Chiang CK, Chen YL, Yang SY, Horng HE, Yang HC, Wu CC* . A noninvasive method to determine the fate of Fe3O4 nanoparticles following intravenous injection using scanning SQUID biosusceptometry. PLoS One 2012;7(11):e48510. [PubMed Abstract]

2012 Yin WH, Wu CC*, Jaw-Wen Chen JW. Registry of Lipid Control and the Use of Lipid-lowering Drugs for Secondary Prevention of Cardiovascular Events in Patients with Established Atherosclerotic Disease in Taiwan: Rationality and Methods. Int J Gerontology 2012; 6:241-6.

2012 Hsu CC, Wu YC, Farh L, Du YC, Tseng WK, Wu CC*, Chang FR. Physalin B from Physalis angulata triggers the NOXA-related apoptosis pathway of human melanoma A375 cells. Food and Chemical Toxicology 2012; 50: 619-624. [PubMed Abstract]

2012 Hsieh WJ, Liang CJ, Chieh JJ, Wang SH, Lai IR, Chen JH, Chang FH, Tseng WK, Yang SY, Wu CC*, Chen YL. In vivo tumor targeting and imaging with anti-vascular endothelial growth factor antibody-conjugated dextran-coated iron oxide nanoparticles. Int J Nanomedicine 2012; 7:2833–2842. [PubMed Abstract]

2012 Huang KW, Yang SY, Hong YW, Chieh JJ, Yang CC, Horng HE, Wu CC* , Hong CY, Yang HC. Feasibility studies for assaying alpha-fetoprotein using antibody- activated magnetic nanoparticles. Int J Nanomedicine 2012 2012; 7:1991–1996. [PubMed Abstract]

2011 Huang KW, Yang SY, Yu CY, Chieh JJ, Yang CC, Horng HE, Hong CY, Yang HC, Wu CC* . Exploration of the relationship between the tumor burden and the concentration of vascular endothelial growth factor in liver-cancer-bearing animals using immunomagnetic reduction assay. J Biomed Nanotechnology 2011; 7:535-41. [PubMed Abstract]

2011 Chieh JJ, Tseng WK, Horng HE, Hong CY, Wu CC* . In-vivo and real-time measurement of magnetic-nanoparticles distribution in animals by scanning SQUID biosusceptometry for biomedicine study. IEEE Transactions on Biomedical Engineering 2011; 58, 2719-2724. [PubMed Abstract]

2011 Yang YF, Wu CC*, Chen WP, Chen YL, Su MJ. Prazosin induces p53-mediated autophagic cell death in H9C2 cells. Naunyn-Schmiedeberg Archives of Pharmacology 2011;384(2):209-16. [PubMed Abstract]

2011 Tseng WK, Chieh JJ, Yang SY, Horng HE, Hong CY, Yang HC, Wu CC*. In-vivo and fast examination of iron concentration of magnetic nano-particles in an animal torso via scanning SQUID biosusceptometry. IEEE Trans. Appl. Supercond. 2011; 21:2250-2253.

2010 Lin CY, Chen YH, Hsu HY, Wang SH, Liang CJ, Kuan II, Wu PJ, Pai PY, Wu CC*, Chen YL. Ganoderma lucidum polysaccharides attenuate endotoxin-induced intercellular cell adhesion molecule-1 expression in cultured smooth muscle cells and in the neointima in mice. Journal of Agricultural and Food Chemistry 2010;58: 9563–9571. [PubMed Abstract]

2010 Hsuan CF, Huang CK, Lin JW, Lin LC, Lee TL, Tai CM, Yin WH, Tseng WK, Hsu KL, Wu CC*. The effect of surgical weight reduction on left ventricular structure and function in severe obesity. Obesity (Silver Spring). 2010;18:1188-93. [PubMed Abstract]

2010 Wei YF, Wu HD, Chang CY, Huang CK, Tai CM, Hung CM, Tseng WK, Wu CC*.The impact of various anthropometric measurements of obesity on pulmonary function in candidates for surgery. Obes Surg. 2010;20:589-94. [PubMed Abstract]

2010 Lee TL, Tseng WK, Hsuang CF, Hwang JC, Wu CC*, Hu PY. Suture knot embolism-a rare complication of percutaneous arterial closure device. Cardiovasc Pathol. 2010;19:63-4. [PubMed Abstract]

2009 Lin SJ, Hsieh FY, Chen YH, Lin CC, Kuan II, Wang SH, Wu CC*, Chien HF, Lin FY, Chen YL. Atorvastatin induces thrombomodulin expression in the aorta of cholesterol-fed rabbits and in TNFalpha-treated human aortic endothelial cells. Histol Histopathol. 2009;24:1147-59. [PubMed Abstract]

2009 Wu CC*, Wang SH, Kuan II, Tseng WK, Chen MF, Wu JC, Chen YL. OxLDL upregulates caveolin-1 expression in macrophages: Role for caveolin-1 in the adhesion of oxLDL-treated macrophages to endothelium. J Cell Biochem. 2009;107:460-72. [PubMed Abstract]

2009 Wang SH, Lin SJ, Chen YH, Lin FY, Shih JC, Wu CC*, Wu HL, Chen YL. Late outgrowth endothelial cells derived from Wharton jelly in human umbilical cord reduce neointimal formation after vascular injury: involvement of pigment epithelium-derived factor. Arterioscler Thromb Vasc Biol. 2009;29:816-22. [PubMed Abstract]

2009 Wu CC*, Liu YB, Lu LS, Lin CW. Imaging reactive oxygen species dynamics in living cells and tissues. Front Biosci (Schol Ed). 2009;1:39-44. [PubMed Abstract]

2009 Hsuan CF, Tseng WK, Yang CH, Lee TL, Hu PY, Wu CC*. Primary Myxosarcoma of the Right Inferior Pulmonary Vein Presenting Clinically as Benign Left Atrial Myxoma With a Concurrent Right Lower Lung Tumor. Circ J. 2009;73:1547-9. [PubMed Abstract]

2009 Lin LC, Wu CC*, Lin MS, Lin SF, and Liu YB. Reducing the cyclic variations of ultrasonic integrated backscatters and myocardial electrical synchronism by reversibly blocking intercellular communications with heptanol. Ultrasound Med Biol. 2009;35:209-18. [PubMed Abstract]

2009 Hsuan CF, Lee TL, Chang HL, Tseng WK, Wu CC*. A retrospective study of statin use and its effectiveness in Taiwanese. Acta Cardiologica Sinica 2009;25:18-25.

2008 Yang SY, Jian ZF, Horng HE, Hong CY, Yang HC, Wu CC*, Lee YH. Dual immobilization and magnetic manipulation of magnetic nanoparticles. J Magn Magn Mater 2008;320:2688-2691.

2008 Chu TS, Weed HG, Wu CC*, Hsu HY, Lin JT, Hsieh BS. A programme of accelerated medical education in Taiwan. Med Teach. 2008;23:1-5. [PubMed Abstract]

2008 Lee TL, Hsuan CF, Chang HL, Wu HMG, Tseng WK, Wu CC*. Is it Cost-Effective to Change Brand-Name to Generic Simvastatin in Taiwan? Acta Cardiologica Sinica 2008;24:191-197.

2008 Yang KC, Su YN, Shew JY, Yang KY, Tseng WK, Wu CC*, Lee YT. Corrections to the LDLR gene polymorphisms identified in a Taiwanese population. J Formos Med Assoc. 2008;107:193. [PubMed Abstract]

2008 Ueng KC, Lin LC, Voon WC, Lin MC, Liu YB, Su HM, Chang PY, Lin TH, Chen WL, Wu CC*, Lai WT, Lin CS.  An eight-week, multicenter, randomized, double-blind study to evaluate the efficacy and tolerability of fixed-dose amlodipine/benazepril combination in comparison with amlodipine as first-line therapy in Chinese patients with mild to moderate hypertension. Blood Press. 2008;17 Suppl 1:24-31. [PubMed Abstract]

2008 Wu CC*, Huang HC, Liu YB, Lin LC, Lin LY, Chen MF, Tsai MC, Gao YL, Yang SY, Horng HE, Yang HC, Tseng WK, Lee TL, Hsuan CF, Pan YF, Lee YH. Two-dimensional propagations of magnetocardiac T wave signals for characterizing myocardial ischemia. Appl. Phys. Lett. 2008; 92: 194104 -1-3.

2008 Wu CC*, Lin LY, Lin LC, Huang HC, Yang YF, Liu YB, Tsai MC, Gao YL, Wang WC, Hung SW, Yang SY, Horng HE, Yang HC, Tseng WYI, Yeh HI, Hsuan CF, Lee TL, Tseng WK. Biofunctionalized magnetic nanoparticles for in vitro labeling and in vivo locating specific biomolecules. Appl. Phys. Lett. 2008; 92: 142504-1-3.

2007 Wu CC*, Wang YM , Lu LS , Sun CW , Lu CW, Tsai MT, Yang CC. Tissue Birefringence of the Hypercholesterolemic Rat Liver Measured with Polarization-sensitive Optical Coherence Tomography. J Biomed Opt. 2007;12:064022.

2007 Wang JY, Chung WP, Kao HL, Lin LC, Wu CC*. Regional Myocardial Contractile Function Change Evaluated by Tissue Doppler Imaging after Primary Angioplasty. Acta Cardiologica Sinica 2007; 23: 89-96.

2007 Yang KC, Su YN, Shew JY, Yang KY, Tseng WK, Wu CC*, Lee YT. LDLR and ApoB Are Major Genetic Cause of Autosomal Dominant Hypercholesterolemia in a Taiwanese Population. J Formos Med Assoc. 2007; 106: 799–807. [PubMed Abstract]

2007 Lu LS, Hung LM, Liao CH, Wu CC* , Su MJ. Effects of Rosiglitazone on Native Low Density Lipoprotein-Induced Respiratory Burst in Circulating Monocytes And on the Leukocyte-Endothelial Interaction in Cholesterol-Fed Rats. Naunyn-Schmiedeberg Archives of Pharmacology. 2007; 375: 251-60. [PubMed Abstract]

2007 Wu CC*, Hong BF, Wu BH, Yang SY, Horng HE, Yang HC, Tseng IWY, Tseng WK, Liu YB, Lin LC, Lu LS, Lee YH. Animal magnetocardiography using superconductive quantum interference device gradiometers assisted with magnetic nanoparticle injection - A sensitive method for early detecting electromagnetic changes induced by hypercholesterolemia. Appl. Phys. Lett. 2007; 90: 054111.

2007 Lu LS, Wu CC*, Hung LM, Chiang MT, Lin CT, Lin CW, Su MJ. Apocynin alleviated hepatic oxidative burden and reduced liver injury in hypercholesterolemia. Liver International. 2007; 27: 529-37. [PubMed Abstract]

1994 吳造中。特輯 /台大內科學講義－第三版/ 無症狀心肌缺氧（Silent myocardial ischemia），(ISBN：957-9201-12-9橘井文化事業)